Assessment of Sensitization to Insect Aeroallergens among Patients with Allergic Rhinitis in Yazd City, Iran
Abstract
The frequency of allergic diseases such as allergic rhinitis is considerable in general population. Insect aeroallergens are important allergens which can induce airway inflammation. The aim of this study was to determine the prevalence of sensitization to insect aeroallergens in allergic rhinitis patients in Yazd as a desert city in Iran.
A cross-sectional study was undertaken on 95 allergic rhinitis patients who were referred to allergy clinic of Yazd city. Skin prick tests (SPT) by standard extracts of three insect aeroallergens including Mosquito, Corn moth, Cockroach and two species of mites as common aeroallergens in allergic rhinitis (Dermatophagoid Farina, Dermatophagoid Peteronysinus) were done.
SPT results showed that the most common insect aeroallergens were: mosquito (32.6%) followed by corn moth (26.3%) and cockroach (13.7%).The prevalence of SPT positive response to Dermatophagoid Peteronysinus, Dermatophagoid Farina were 8.4% and 7.4%, respectively. These results demonstrated that sensitization to insect aeroallergens was significantly more common compared to mites in patients with allergic rhinitis in Yazd city, a city surrounded by deserts.
High prevalence of skin reactivity to mosquito and corn moth as insect aeroallergens in Yazd city with hot and dry climate in contrast to humid regions such as north of Iran, where mites are more frequent, indicates differences in the prevalence of aeroallergen reactivity in various areas with different climates. Our study could highlight the importance of insect aeroallergens for clinicians for better diagnosis and management of patients with allergic rhinitis.
1. Orban NT,Saleh H and Durham a SR. Allergy and Non- Allergic Rhinitis. In: Adkinson NF.Bochner BS.Busse WW. Hoglgate ST, Lemanske Jr RF, Simons FER. Middleton's allergy: principles & practice.;vol[2].7th ed. Mosby :Philadelphia. USA: 2009: 973-90.
2. Tang EA, Matsui E, Wiesch DG and Samet JM.Epidemiology of Asthma and Allergic diseases. In: Adkinson NF, Bochner BS, Busse WW, Hoglgate ST, Lemanske Jr RF, Simons FER. Middleton's allergy: principles & practice; vol[2].7th editors. Mosby: Philadelphia. USA: 2009: 715-68.
3. Kashef S, Kashef MA, Eghtedari F. Prevalence of aeroallergens in allergic rhinitis in Shiraz. Iran J Allergy Asthma Immunol 2003; 2(4):185-8.
4. Hwang KY, Park JS, Ahn HC, Nam HS. Prevalence of arthropod antibodies in Korean patients with allergic rhinitis. Korean J Parasitol 2001; 39(2):197-9.[Abstract]
5. Mesdaghi M, Pourpak Z, Moein M. The state of cockroachallergy among patients with cockroach allergy in Iran. Tehran University Medical Journal(TUMJ) 2005;63(8):667-73.[Abstract]
6. Farhoudi A, Pourpak Z, Mesdaghi M, Chavoshzadeh AKZ.The study of Cockroach allergy in Iranian children with asthma. Acta Medica Iranica 2003; 41(3):150-5.
7. Katial RK. Coakroach allergy. Immunol Allergy Clin North Am 2003; 23(3):483-99.
8. Bousquet J, Khaltaev N, Cruz A, Denburg J, Fokkens W, Togias A, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA (2)LEN and AllerGen). Allergy 2008; 63 (Suppl 86):8-160.
9. Bemoly P, Bousquet J. Middleton's allergy: principles & practice: Mosby USA: 2009. 7th edition; 1267-80. Chapter 71: In vivo methods for the study of allergy.
10. Amoli K, Cunnington A. House dust mites in Iran. Clin Allergy 1977; 7(1):93-101.
11. Ghaffari J, Khademloo M, Saffar M, Rafiei A, Masiha F.Hypersensitivity to house dust mite and cockroach is the most common allergy in north of iran. Iran j immunol 2010; 7(4):234.[Absract]
12. Sritipsukho P. Aeroallergen sensitivity among Thai children with allergic respiratory diseases: a hospital- based study. Asian Pac J Allergy Immunol 2010; 22(2-3):91-5.
13. Li Z, Furong M, Li W, Zhongqi L, Yan Y, Ping Z.Analysis of SPT with standardized antigens in patients with allergic rhinitis. Chinese Archives of Otolaryngology-head and Neck Surgery 2007; 1.
14. Bener A, Safa W, Abdulhalik S, Lestringant GG. An analysis of SPT reactions in asthmatics in a hot climate and desert environment. Allerg Immunol(Paris) 2002;34(8):281-6.[Absract]
15. Platts-Mills T AE, Adkinson N F, Bruce JR,Bochner S. Middleton's allergy: principles & practice: Mosby USA;2009. 7th edition; 539-56. chapter: Indoor Allergens.
16. Parveen T, Begum N, Begum S. Allergen Skin Test Reactivity and Serum Total IgE Level in Adult Bronchial Asthmatic Patients. Journal of Bangladesh Society of Physiologist 2009; 4(1):1-6.
17. Liam CK, Loo KL, Wong CM, Lim KH, Lee TC. SPT reactivity to common aeroallergens in asthmatic patients with and without rhinitis. Respirology 2002; 7(4):345-50.
18. Montealegre F, Meyer B, Chardon D, Vargas W, Zavala D, Hart B, et al. Comparative prevalence of sensitization to common animal, plant and mould allergens in subjects with asthma, or atopic dermatitis and/or allergic rhinitisliving in a tropical environment. Clin Exp Allergy 2004;34(1):51-8.
19. Adanijo A, Bandele E. Cockroach hypersensitivity in asthmatics in Lagos, Nigeria. East Afr Med J 2009;77(11): 622-6.
20. Dowaisan A, Al-Ali S, Khan M, Hijazi Z, Thomson MS, Ezeamuzie CI. Sensitization to aeroallergens among patients with allergic rhinitis in a desert environment. Ann Allergy Asthma Immunol 2000; 84(4):433-8.
21. Okuda M, Usami A, Itoh H, Ogino S. Nationwide investigation of insect allergy in patients with allergic rhinitis. Nippon Jibiinkoka Gakkai Kaiho 2002;105(12):1181-8.
22. Maclaren WR, Eisenberg BC. Reactions to Insect Allergens. Calif Med 1960; 93(4):224-6.
23. Skjold T, Nielsen SC, Adolf K, Hoffmann HJ, Dahl R, Sigsgaard T. Allergy in bakers’ apprentices and factors associated to non-participation in a cohort study of allergic sensitization. Int Arch Occup Environ Health 2007; 80(5):458-64.
24. Villalta D, Martelli P, Mistrello G, Roncarolo D, Zanoni D. Bee moth (Galleria mellonella) allergic reactions are caused by several thermolabile antigens. Allergy 2004;59(9):1002-5.
25. Asero R, Mistrello G. Respiratory and Skin Allergy to Galleria mellonella(Bee Moth). Int Arch Allergy Immunol 2008; 145(4):340-2.
26. Mungan D, Celik G, Sin B, Bavbek S, Demirel Y, Misirligil Z. Characteristic features of cockroach hypersensitivity in Turkish asthmatic patients. Allergy 1998; 53(9):870-3.
27. Alp H, Yu BH, Grant EN, Rao V, Moy JN. Cockroach allergy appears early in life in inner-city children with recurrent wheezing. Ann Allergy Asthma Immunol 2001;86(1):51-4.
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Issue | Vol 11, No 3 (2012) | |
Section | Articles | |
Keywords | ||
Allergic rhinitis Insect aeroallergens Skin prick test (SPT) |
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