Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 11 3 2012 09 15 253 258 EN Mohammad Hassan Bemanian Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Pediatrics, Division of Allergy and Clinical Immunology, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Narges Alizadeh Korkinejad Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Shima Shirkhoda Department of Pediatrics, Division of Allergy and Clinical Immunology, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mohammad Nabavi Department of Asthma and Allergy, Tehran University of Medical Sciences, Hazrat Rasoul Hospital, Tehran, Iran Zahra Pourpak Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran 2015 10 16 The  frequency of  allergic diseases such  as allergic rhinitis is considerable in general population. Insect aeroallergens are important allergens which can induce airway inflammation. The aim of this study was to determine the prevalence of sensitization to insect aeroallergens in allergic rhinitis patients in Yazd as a desert city in Iran. A cross-sectional study was undertaken on 95 allergic rhinitis patients who were referred to allergy clinic of Yazd city. Skin prick tests (SPT) by standard extracts of three insect aeroallergens including Mosquito,  Corn  moth,  Cockroach  and  two  species of  mites  as common  aeroallergens in allergic rhinitis (Dermatophagoid  Farina, Dermatophagoid Peteronysinus) were done. SPT results showed that the most common insect aeroallergens were: mosquito (32.6%) followed by corn  moth  (26.3%) and cockroach (13.7%).The prevalence of SPT positive response to Dermatophagoid Peteronysinus, Dermatophagoid Farina were 8.4% and 7.4%, respectively. These  results  demonstrated  that  sensitization  to  insect  aeroallergens was significantly more common compared to mites in patients with allergic rhinitis in Yazd city, a city surrounded by deserts. High prevalence of skin reactivity to mosquito and corn moth as insect aeroallergens in Yazd city with hot and dry climate in contrast to humid regions such as north of Iran, where mites are more frequent, indicates differences in the prevalence of aeroallergen reactivity in various areas with different climates. Our  study could highlight the importance of insect aeroallergens for clinicians for better  diagnosis and management of patients with allergic rhinitis. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/554 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/554/489