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Author Guidelines

The Iranian Journal of Allergy, Asthma and Immunology  (IJAAI),  an  international  peer- reviewed  scientific and  research journal, seeks  to publish  original  papers,  selected  review  articles, case-based reviews, and other articles of special interest related to the fields of asthma, allergy and immunology. The journal is an official publication of  the  Iranian  Society  of  Asthma  and  Allergy (ISAA), which is supported by the Immunology, Asthma and Allergy Research Institute (IAARI) and published by Tehran University of Medical Sciences (TUMS). The journal seeks to provide its readers with the highest quality materials published through a process of careful peer reviews and editorial comments. All papers are published in English.

The   IJAAI   uses   the   World   Association   of Medical Editors’ definition of editorial freedom and is a member of the Committee on Publication Ethics (COPE).  The  journal  adopts  COPE’s  guidelines upon encounter with ethical misbehavior.

Manuscript Submission
Authors    are     requested    to     submit     their manuscripts online at The system assigns a number to manuscripts and authors are requested to mention the manuscript number on all correspondence with the journal.
The Instructions to Authors of this journal are in accordance with the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (
The corresponding author and all other authors of  the  manuscript  should  sign  under  their  own names in the cover letter before submitting the manuscript to this journal for publication. Corresponding author should enter all authors’ names, affiliations and emails while submitting the manuscript. The failure to do these will cause fast rejection of the paper.
This online manuscript submission and  review system  offers   authors   the   option   to   track   the progress of the review process of manuscripts in real time. The average turn-around times before you receive the first decision in this journal is approximately 8 weeks. In case you encounter any difficulties while submitting your manuscript online, please contact the editorial office (E-mail:

Manuscript Preparation
Manuscripts should be typed single-spaced with one-inch margins. All tables, figure legends, and references, must be typewritten with single spacing. All  submitted  components  of  the  manuscript  are non-returnable,  unless  a   special  arrangement  is made in advance with the Editors. Arrange the manuscript with the following components: (1) Title page, (2) Abstract, (3) Introduction, (4) Materials/Patients and Methods, (5) Results, (6) Discussion, (7) References, (8) Acknowledgements, (9) Conflict of Interest, (10) Tables, and Figures and Figure   Legends.   Please   place   all   illustrations, figures, and tables within the text at the appropriate points, rather than at the end.

Authors should number all pages of the manuscript consecutively, beginning with  the  title page. In addition, the editor requires authors to provide a cover letter in which they specifically state their written assurance of the following:

(1) The submitted paper is an original and unpublished work in which the listed authors have all made important contributions explaining the contributions in detail;

(2) The authors have not submitted the same material or portions thereof for consideration of publication in any other journal for which a decision regarding publication is pending, and no such additional submission will be made before completion of the review process by the IJAAI;

(3) The authors must further guarantee that, once their  material  has  been  accepted  for  publication by the journal, they will not make submission of the same material or portions thereof to another journal.

The editors also require that the authors be responsible   for   the   linguistic   and   grammatical editing of manuscripts before submission to the journal. Only minor editing of the manuscript may be undertaken by the editor. All authors should adhere to the following instructions for submission of manuscripts to the IJAAI. 

Cover Letter

The authors should provide the assurances listed above. The authors must always make a complete statement to the editor about all previous reports and submissions that might be regarded as redundant or duplicate publications (including meeting presentations, registries, etc). If redundant or duplicate publication is attempted without notification, prompt rejection of the manuscript should   be   expected.   In   addition,   authors   are welcome to suggest three to five referees for their paper; however, the editors cannot guarantee assignment of a particular reviewer to a paper. Authors can provide editors with the names of persons they feel should not be asked to review a manuscript because of potential, usually  professional, conflict of interest. Any unusual circumstances surrounding the research or explanations  for  deviation  from  standard procedures or format should be explained in  the cover letter. The authors are required to submit an ethics committee approval as a supplementary file and write the number and date in the cover letter. The cover letter should be signed by all authors. 


When using abbreviations, write the full name of  the  abbreviated  item  followed  by  the abbreviation in parentheses at the point of first mention of the abbreviation within the abstract and the  body of  the  manuscript: e.g.,  "cell  mediated immunity (CMI)". Do not use abbreviations in the title of the manuscript. Abbreviations may be used in figures and tables, but such abbreviations must be explained in the figure legend or a footnote to the table unless the abbreviation is a stand ard unit of measurement.

Title Page

The  title  page  should  contain  the  following information: (1)  The full title of the manuscript, not to exceed 120 characters. No abbreviations are acceptable in the full title. If the work involves the use of an experimental model, the animal species involved must be included in the title. (2) The full names of all authors. Authorship credit should be based on a) substantial contributions to the conception or design, or the acquisition, analysis, or interpretation of data for the work; b) drafting the article or revising it critically for important intellectual content; and  c)  final approval of the version to be published; and d) agreement to  be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Authors should meet conditions a, b, c and d. (3) The department and institution where work was performed, as well as the affiliations of the individual authors (more than

2 affiliations are not accepted for each author) . (4) Source(s) of support, indicating any grants, equipments, drugs, or all of these for the study. (5) The name and address of the author responsible for correspondence.  Include  the  name,  mailing address,  telephone  and  fax  numbers,  and  e -mail address. (6) A shortened version of the title that is

45 characters or less to be used as a running title. (7) Word counts for the text only, excluding abstract,  acknowledgements,  figures,  figure legends, tables and references. (8) The number of figures and tables should be noted on the title page. 

Original Articles

Scientific articles should conform to the usual structure  of  abstract,  introduction, materials/patients and methods, results, discussion, acknowledgements, conflict of interest, references, tables, figures and legends for figures. Number the pages starting with the title page.


The abstract must be limited to 250 words. Do not use footnotes or references in the abstract. Include a brief description of the goal, materials and methods, findings, and conclusion of the study. Abstracts of clinical trials should include items that CONSORT group has identified as essential (

Three  to  nine  keywords  for  indexing  should be   given   by   the author(s)   together   with   the abstract.  They  should  be  placed  in alphabetical order and, when possible, adjusted to the medical subject headings (MESH) at

Introduction,  Materials/Patients  and  Met hods, Results, and Discussion

Introduction: containing the reasons for doing the   work   and   specific   purpose   or   research objective; Methods: sufficient information must be included to permit reproduction of experimental work. Patients and Methods are used in the clinical sciences  articles  and  Materials  and  Methods  are used in the basic and laboratory sciences articles; Results: data and findings of research which should be given concisely; the use of tables and figures are encouraged but should not replicate the data presented  in  the  text;  Discussion:     should  not repeat results.

Include within the methods, a description of the ethical  guidelines  that  were  followed  for  human and animal studies. If appropriate, provide citation of   institutional   review   by   human   or   animal research committees. Also describe any hazardous procedures  or  chemicals  involved  in  the  studies and what precautions were taken to avoid injury to subjects or investigators. Within the Methods section, provide a brief but complete descrip tion of the statistical methods used including which tests were used for analysis of which variables. Specify the computer software used. Drugs, medication, or other material should be listed as generic items. If brand names are used, they should be placed after the generic name in parenthesis with the manufacturer's name, city, and state or country. Restrict all comments and discussion to the Discussion section. 


All  contributions  that  do  not  meet  authorship criteria   should   be   listed   in   acknowledgements section. Sources of financial support should be mentioned in this section, if required. The organization(s) which financially and otherwise supported the research project should be acknowledged, in order of priority (if necessary).

Conflict of Interest

Conflict of interest should be mentioned or ruled out.


The  IJAAI  has  now  adopted  the  Vancouver Reference System and all submitted manuscripts should be in this style.

Cite references in  text in  order of  appearance using Arabic numerals in parentheses for citations. Place the reference list at the end of the final text page. References should  be  listed  in  text  citation number order and  must be  single-spaced. List  all authors when six or fewer; when seven or more, list the first six and add “et al”. All published materials, including brief  communications and  letters  to  the editor must be cited in the References section.

Manuscripts accepted but not yet published can also be included in the references; designate the journal followed by 'in press' (in parentheses). References   to    unpublished   material,   such   as personal  communications  and   unpublished   data, must be placed within the text and not cited in the Reference section. Personal communication and unpublished   data   must   include   the   individual's name, location, and month and year of communication as appropriate. Use Index Medicus abbreviations for journals that are indexed; if a journal is not indexed, use full name. If using reference managing software such as Reference Manager, EndNote, or ProCite, choose the style for “Vancouver  style,”  which  most  closely approximates our style. Please include volume, number and page range whenever possible.

Journal Article

*  Saghafi S,  Pourpak Z,  Glocker C,  Nussbaumer  F, Babamahmoodi A, Grimbacher B, et al. The Diagnosis of Hyper Immunoglobulin E Syndrome Based on Project Management.   Iran   J   Allergy  Asthma   Immunol   2015; 14(2):126-132.

* Bahrami H, Daneshmandi S, Heidarnazhad H, Pourfathollah AA. Lack of Association between Toll Like Receptor-2 and Toll Like Receptor-4 Gene Polymorphisms and Other Feature in Iranian Asthmatics Patients. Iran J Allergy Asthma Immunol 2015; 14(1):48-54.

Book Chapter

Kirk Osterlan C, Farhoudi A. Assessment of immunodeficiency. In: Nakamura RM, Burek CL, Cook L,  Folds  JD,  Server  JL,  editors.  Clinical  diagnostic immunology: Protocols in quality assurance and standardization. USA: Blackwell Science Pty Ltd, 1998: 197-208.


Each  table  should  be  typewritten  with  single spacing and numbered in order of citation in the text with Arabic numerals. Each table should have a concise   heading   that   makes   it   comprehensible without reference to the text of the article. Use horizontal lines only at the top and bottom of the table and between column headings and the body of the table. Use no vertical lines. Explain any abbreviations in a footnote to the table.

Figures and Figure Legends

Figures must be submitted as electronic files in a format (for example, JPEG or GIF) that will produce high-resolution images  in  the  web version  of  the journal.  The editors and publisher reserve the right to reject  illustrations or  figures  based  upon  poor quality of submitted materials. Figure  legends  should  be  typed  using  single spacing with explanations for symbols, arrows, or letters used to identify parts of illustrations. Explain any abbreviations in figure legends.

Brief Communications

Brief  Communications  (of  no  more  than  2000 words and two tables and/or figures) will be considered for publication on an accelerated schedule.

Review Articles

The Journal welcomes review articles covering basic or clinical allergy, asthma, and immunology that  are  likely  to  be  of  interest  to  the broad readership of the journal. Authors of review articles should include a section describing the methods of selecting,  extracting  and synthesizing data,  which are also summarized in the abstract.

Case-based Reviews

Short   reports   of   clinical   interest   and   brief individual   case reports   are   welcome   but   only accepted in a limited number.

Letters to the Editor

Letters of opinion about articles published in the IJAAI and other current topics or short reports of clinical or laboratory interest are accepted for consideration for publication. These should not exceed 1000 words and 15 references and one table and/or figure without an abstract or subheadings and subheadings. The editor reserves the right to  edit such  letters  and  to  use  his  discretion  in  their selection for publication.

Ethics and Consent

Authors  must  state  that  the  protocol  for  the research project has  been approved by a  suitably constituted Ethics Committee of the institution within which the work was undertaken and that it conforms to the provisions of the Declaration of Helsinki in 1995 (as revised in Edinburgh 2000).

The clinicians, who conduct a clinical trial on human subjects and wish to publish the results of their investigations in this journal, should have obtained permission for their clinical trial from Iranian Registry of Clinical Trials (IRCT) or other well-known clinical trials registries. IRCT number is mandatory for researches performed in Iran.

All studied subjects should be completely informed   about   the   procedure   and   informed consent should be obtained from all participants. The journal reserves the right to request the related documents. 

Revision of Manuscripts

Revisions must be submitted electronically through the manuscript submission system at Revisions must  include  the responses to comments and also a marked revised manuscript. Our preferred method of showing changes is Microsoft Word's Track Changes feature. Alternately, added text should be underlined, and any text that was deleted should be indicated by strikethrough formatting. 


The  Agreement is  made  with  the  IJAAI.  The Agreement is for the article submitted by authors for publication in the IJAAI.

To enable publishing the article in the journal, the  ownership  of  copyright  must  be  established. The authors should read and complete the form and send  one  copy to  the  journal office  by email  or upload it on the website as a supplementary file . There  are  explanatory  notes  to  this Agreement, which also form part of the Agreement.

In consideration of the publication of the article in the journal, authors warrant and undertake: 

a. that the article is an original work, has not been published before and is  not being considered for publication elsewhere in its final form either in printed or electronic form.

b. that author has obtained permission from the copyright holder to reproduce in the article (in all media  including print and electronic form) material not owned by author, and that author has acknowledged the source;

c. that this article contains no violation of any existing copyright or other third party right or any material of  an  obscene,  indecent  or  otherwise  unlawful nature and that to the best of my knowledge this article does not infringe the rights of others;

d. that author will indemnify and keep indemnified the Editors, the Iranian Journal of Allergy, Asthma and Immunology   against   all   claims   and   expenses (including legal  costs  and  expenses) arising from any breach of this warranty and the other warranties on my behalf in this Agreement;

e. that in the case of a multi-authored article, author has obtained copyright assignment from all co- authors, in writing, and authorization to enter into this  Agreement  on  their  behalf  and  that  all  co - authors have read and agreed the above warranties;

Note: The manuscript cannot be processed for publication until the publisher has received this signed form. If the manuscript is not published by the IJAAI, this letter will not take effect.


Proofs will  be  sent  to  the  author and  should  be returned within 72 hours of receipt through the website. Corrections should be restricted to typesetting errors. The publisher will do everything quickly and accurately as possible. Therefore, it is important to ensure that all of your corrections are returned to us in one all-inclusive e-mail. Subsequent additional corrections will not be possible, so please ensure that your first communication is complete. The returned proof is your formal confirmation to publish the paper. Metadata of papers should be checked by the corresponding author at this stage.

Fast Track Review of Papers

In the handling of all manuscripts for publication, the editors will strive to provide the most rapid turnaround possible in the review process. Authors may request rapid review of material  felt  to  be  of  critical  importa nce  to  the field.  The  request  must  state  clearly  why  the authors believe rapid review is warranted and must be submitted to the editors in written form at the time of manuscript submission. Manuscripts accepted by the editors for rapid review might be published in the next scheduled issue of the journal or at the editors' discretion. Manuscripts submitted for rapid communication that require extensive revision will be rejected and the authors can resubmit the articles for regular publication.  The journal  requests  authors  for  an  extra  charge  for fast-track review of their papers. The requests can be sent by email to the editorial office. 

Publication Charge

The editorial committee reserves the right to charge authors for extra costs for English editi ng, if necessary. 

Journal Subscription

In order to subscribe for hard copies,  please contact journal office for subscription rates and processes.


Submission Preparation Checklist

As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.

  1. The submission has not been previously published, nor is it before another journal for consideration (or an explanation has been provided in Comments to the Editor).
  2. The submission file is in OpenOffice, Microsoft Word, RTF, or WordPerfect document file format.
  3. The copyright form is signed and will be uploaded during the submission process as a supplementary file.
  4. The text is single-spaced; uses a 12-point font; employs italics, rather than underlining (except with URL addresses); and all illustrations, figures, and tables are placed within the text at the appropriate points, rather than at the end.
  5. The text adheres to the stylistic and bibliographic requirements outlined in the Author Guidelines, which is found in About the Journal.
  6. If submitting to a peer-reviewed section of the journal, the instructions in Ensuring a Blind Review have been followed.

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