Gene Expression Profiling of Toll-Like Receptor 4 and 5 in Peripheral Blood Mononuclear Cells in Rheumatic Disorders: Ankylosing Spondylitis and Rheumatoid Arthritis
-
Simin Almasi
,
Saeed Aslani
,
Hadi Poormoghim
,
Ahmad Reza Jamshidi
,
Shiva Poursani
,
Mehdi Mahmoudi
Abstract
No Abstract###
1. Botos I, Segal DM, Davies DR. The structural biology of Toll-like receptors. Structure 2011; 19(4):447-59.
2. Braun J, Sieper J. Ankylosing spondylitis. Lancet 2007; 369(9570):1379-90.
3. Colbert RA, DeLay ML, Klenk EI, Layh‐Schmitt G. From HLA‐B27 to spondyloarthritis: a journey through the ER. Immunol Rev 2010; 233(1):181-202.
4. Lories RJ, Schett G. Pathophysiology of new bone formation and ankylosis in spondyloarthritis. Rheum Dis Clin North Am 2012; 38(3):555-67.
5. Raffeiner B, Dejaco C, Duftner C, Kullich W, Goldberger C, Vega SC, et al. Between adaptive and innate immunity: TLR4-mediated perforin production by CD28null T-helper cells in ankylosing spondylitis. Arthritis Res Ther 2005;7(6):R1412-20.
6. De Rycke L, Vandooren B, Kruithof E, De Keyser F, Veys EM, Baeten D. Tumor necrosis factor α blockade treatment down‐modulates the increased systemic and local expression of toll‐like receptor 2 and toll‐like receptor 4 in spondylarthropathy.Arthritis Rheum 2005; 52(7):2146-58.
7. Roelofs MF, Boelens WC, Joosten LA, Abdollahi- Roodsaz S, Geurts J, Wunderink LU, et al. Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis. Arthritis Rheum 2006;176(11):7021-7.
8. Assassi S, Reveille JD, Arnett FC, Weisman MH, Ward MM, Agarwal SK, et al. Whole-blood gene expression profiling in ankylosing spondylitis shows upregulation of toll-like receptor 4 and 5. J Rheumatol 2011; 38(1):87-98.
9. Shi D, Das J, Das G. Inflammatory bowel disease requires the interplay between innate and adaptive immune signals. Cell Res 2006; 16(1):70-4.
10.Moll J, Wright V. New York clinical criteria for ankylosing spondylitis. A statistical evaluation. Ann Rheum Dis 1973; 32(4):354-63.
11.Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol 1994; 21(12):2286-91.
12.Calin A, Garrett S, Whitelock H, Kennedy L, O'hea J, Mallorie P, et al. A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumato 1994; 21(12):2281-5.
13.Jenkinson TR, Mallorie PA, Whitelock H, Kennedy LG, Garrett S, Calin A. Defining spinal mobility in ankylosing spondylitis (AS). The Bath AS Metrology Index. J Rheumatol 1994; 21(9):1694-8.
14.Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative CT method. Nat Protoc 2008; 3(6):1101-8.
15.Takeda K, Akira S. Toll-like receptors in innate immunity. Inter Immunol 2005;17(1):1-14.
16.Radstake TR, Roelofs MF, Jenniskens YM,Oppers‐Walgreen B, van Riel PL, Barrera P, et al. Expression of Toll‐like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin‐12 and interleukin‐18 via interferon‐γ. Arthritis Rheum 2004; 50(12):3856-65.
17.Kerfoot SM, Long EM, Hickey MJ, Andonegui G, Lapointe BM, Zanardo RC, et al. TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease. J Immunol 2004; 173(11):7070-7.
18.Taurog JD, Richardson JA, Croft J, Simmons WA, Zhou M, Fernández-Sueiro JL, et al. The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats. J Exp Med 1994; 180(6):2359-64.
19.Brown M, Laval S, Brophy S, Calin A. Recurrence risk modelling of the genetic susceptibility to ankylosing spondylitis. J Exp Med 2000;59(11):883-6.
20.Rhee SH, Im E, Riegler M, Kokkotou E, O'Brien M, Pothoulakis C. Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci U S A 2005; 102(38):13610-5.
21.Lai NS, Yu HC, Chen HC, Yu CL, Huang HB, Lu MC. Aberrant expression of microRNAs in T cells from patients with ankylosing spondylitis contributes to the immunopathogenesis. Clin Exp Immunol 2013; 173(1):47-57.
22.Yang ZX, Liang Y, Zhu Y, Li C, Zhang LZ, Zeng XM, et al. Increased expression of Toll‐like receptor 4 in peripheral blood leucocytes and serum levels of some cytokines in patients with ankylosing spondylitis. Clin Exp Immunol 2007; 149(1):48-55.
| Files | ||
| Issue | Vol 15, No 1 (2016) | |
| Section | Letter to the Editor | |
| Keywords | ||
| Ankylosing spondylitis Gene expression HLA-B27 antigen Rheumatoid arthritis Toll-Like Receptor 4 Toll-Like Receptor 5 | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
