The Effect of Preventive Immunization on the Incidence of Allergic Conditions
-
Grażyna Dulny
,
Adam J. Sybilski
,
Marta Zalewska
,
Filip Raciborski
,
Jarosław Komorowski
,
Barbara Piekarska
,
Agnieszka Lipiec
,
Bolesław Samoliński
Abstract
The purpose of this study was to assess the effect of preventive immunization on the incidence of allergies in Poland.18617 (53.8% female, 24.2% 6-7 years old, 25.4% 13-14 years old, 50.4% 20–44 years old) were selected by stratified cluster sampling method in 8 cities and 1 rural area. 4783 of whom underwent objective outpatient screening assessments. Study subjects were evaluated for any association between preventive immunization against rubella, measles, typhoid fever, smallpox and incidence of atopic dermatitis, allergic rhinitis, and asthma.There was no increased risk of allergy incidence in the majority of vaccinated subjects against rubella, measles, typhoid fever, or smallpox (OR from 0.42 (ppppp=0.005), varicella (OR=1.18; p=0.003); rhinitis and AR following vaccination against measles (respectively OR=1.22; pp=0.0002). No higher risk of allergic diseases was demonstrated in vaccinated individuals diagnosed by doctor in an outpatient setting.These data do not demonstrate a causal relationship between vaccinations and allergic conditions.
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| Files | ||
| Issue | Vol 14, No 4 (2015) | |
| Section | Original Article(s) | |
| Keywords | ||
| Allergy Immunization Measles Rubella Smallpox Vaccination | ||
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