Articles
 

Exercise Induced Changes in Spirometry and Impulse Oscillometry Measurements in Persistent Allergic Rhinitis

Abstract

The Link between allergic rhinitis and asthma is well known. Bronchial hyperreactivity (BHR) may be present in rhinitis. The present study was aimed to compare airway responses in patients  with rhinitis symptoms alone following exercise challenge, and to  determine relationship of two different respiratory function tests.
98 subjects with rhinitis were investigated by spirometry and impulse oscillometry before and after exercise challenge.
No  significant difference was detected  between spirometry and  impulse oscillometry measurements  before  and  after  exercise challenge in  subjects  with  rhinitis  alone.  No correlation between spirometry and impulse oscillometry indices was found in pre and post- exercise stages.
We therefore conclude that exercise challenge is not an appropriate test to determine airway hyperresponsive in subjects with rhinitis symptoms alone and findings of spirometry and impulse oscillometry are not interrelated.

1. Passalacqua G, Ciprandi G, Canonica GW. United airway diseases: therapeutic aspects. Thorax 2000; 55 (Suppl2):S26-7.
2. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 Update (in collaboration with the World Health Organization, GA2LEN and AllerGen). Allergy 2008; 63 Suppl 86:8-160.
3. Corren J. Allergic rhinitis and asthma: how important is the link? J Allergy Clin Immunol 1997; 99(2): S781-6.
4. Corren J. The connection between allergic rhinitis and bronchial asthma. Curr Opin Pulm Med 2007; 13(1): 13-8.
5. Ciprandi G, Cirillo I, Vizzaccaro A, Milanese M, Tosca MA. Airway function and nasal inflammation in seasonal allergic rhinitis and asthma. Clin Exp Allergy 2004;34(6):891-6.
6. Plaschke PP, Janson C, Norrman E, Björnsson E, Ellbjär S, Järvholm B. Onset and remission of allergic rhinitis and asthma and the relationship with atopic sensitization and smoking. Am J Respir Crit Care 2000; 162 (3 Pt 1):920-4.
7. Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, et al. Interpretative strategies for lung function tests. Eur Respir J 2005; 26(5):948-68.
8. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, et al. Standardisation of spirometry. Eur Respir J 2005; 26(2):319-38.
9. Hamid Q, Song Y, Kotsimbos TC, Minshall E, Bai TR, Hegele RG, et al. Inflammation of small airways in asthma. J Allergy Clin Immunol 1997; 100(1):44-51.
10. Bjermer L. Past and future perspectives in the asthma treatment. Resp Med 2001; 95(9):703-719.
11. Ciprandi G, Cirillo I, Vizzaccaro A, Tosca M, Passalacqua G, Pallestrini E, et al. Seasonal and perennial allergic rhinitis: is this classification adherent to real life? A population based study. Allergy 2005; 60(7):882-7.
12. Ciprandi G, Cirillo I, Klersy C, Marseglia GL, Vizzaccaro A, Pallestrini E, et al. Role of FEF25-75 as an early marker of bronchial impairment in patients with seasonal allergic rhinitis. Am J Rhinol 2006; 20(6):641-7.
13. Katelaris CH. Allergic rhinitis and asthma: epidemiological evidence for the link. Clin Exp All Rev 2003; 3(1):5-8.
14. Townley RG, Ryo UY, Kolotkin BM, Kang B. Bronchial sensitivity to methacholine in current and former asthmatic and allergic rhinitis patients and control subjects. J Allergy Clin Immunol 1975; 56(6):429-42.
15. Braman SS, Barrows AA, DeCotiis BA, Settipane GA, Corrao WM. Airways hyper-responsiveness in allergic rhinitis. A risk factor for asthma. Chest 1987; 91(5):671-4.
16. Verdiani P, Di Carlo S, Baronti A. Different prevalence and degree of nonspecific bronchial hyperreactivity in rhinitis. J Allergy Clin Immunol 1990; 86(4 Pt 1):576-82.
17. Cirillo I, Pistorio A, Tosca M, Ciprandi G. Impact of allergic rhinitis on asthma: effects on bronchial hyperreactivity. Allergy 2009; 64(3):439-44.
18. Macklem PT, Mead J. Resistance of central and peripheral airways measured by a retrograde catheter. J Appl Physiol 1967; 22(3):395-401.
19. Hogg JC, Macklem PT, Thurlbeck WM. Site and nature of airway obstruction in chronic obstructive lung disease. N Engl J Med 1968; 278(25):1355-60.
20. Green M. Treating large and small airways. Int J Clin Pract Suppl 1998; 96:2-4.
21. Fisher AB, DuBois AB, Hyde RW. Evaluation of the forced oscillation technique for the determination of resistance to breathing. J Clin Invest 1968; 47(9):2045-57.
22. Oostveen E, MacLeod D, Lorrino H, Farre´ R, Hantos Z,
Desager K, et al. The forced oscillation technique in clinical practice: methodology, recommendations and future developments. Eur Respir J 2003; 22(6):1026-41.
23. Bohadana AB, Peslin R, Megherbi SE, Teculescu D,
Sauleau EA, Wild P, et al. Dose-response slope of forced oscillation and forced expiratory parameters in bronchial challenge testing. Eur Respir J 1999; 13(2):295-300.
24. Goldman MD. Clinical application of forced oscillation.Pulm Pharmacol Ther 2001; 14(5):341-50.
25. Arets HG, van der Ent CK. Measurements of airway mechanics in spontaneously breathing young children. Paediatr Respir Rev 2004; 5(1):77-84.

Files
IssueVol 11, No 3 (2012) QRcode
SectionArticles
 
Keywords
Bronchial provocation tests Oscillometry Respiratory tract diseases Rhinitis Spirometry

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Arshi S, Nabavi M, Babaie D, Bahrami A, Ghalehbaghi B. Exercise Induced Changes in Spirometry and Impulse Oscillometry Measurements in Persistent Allergic Rhinitis. Iran J Allergy Asthma Immunol. 1;11(3):259-266.