Autoimmune Diseases Co-Existing with Hepatitis C Virus Infection


Autoimmunity and viral infections are closely associated fields, and viruses have been proposed as a likely aetiological, contributory or triggering factors of systemic autoimmune diseases. Hepatitis C virus seems to be the virus usually associated with the appearance of autoimmune diseases, and the relationship between chronic hepatitis C virus infection and some autoimmune disease has been studied. For some of these disorders their association with hepatitis C virus infection is well recognized while for others it remains probable or weak. Examples of autoimmune phenomena observed in chronic hepatitis C virus infection include rheumatoid arthritis, thyroid disease, cryoglobulinaemia, immune thrombocytopenic purpura, systemic lupus erythematosus and sjogren syndrome. To date, the etiological role and the pathogenetic involvement of the hepatitis C infection remains unknown.The aim of this study is to assess the presence of different autoimmune manifestations of hepatitis C virus infection reported in literature.

IssueVol 9, No 4 (2010) QRcode
Autoimmunity Hepatitis C Virus Immune Mediated Disease

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How to Cite
Jadali Z, Alavian S-M. Autoimmune Diseases Co-Existing with Hepatitis C Virus Infection. Iran J Allergy Asthma Immunol. 1;(No. 4):191-206.