Review Article

Montelukast and Coronavirus Disease 2019: A Scoping Review


Coronavirus disease 2019 (COVID-19) is an emerging worldwide issue, that has affected a large number of people around the world. So far, many studies have aimed to develop a therapeutic approach against COVID-19. Montelukast (MK) is a safe asthma controller drug, which is considered as a potential antiviral drug for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This review has a systematic approach to investigate the reports on the use of MK as a part of treatment or a prophylactic agent in COVID-19. The search was conducted in PubMed, Web of Science, and Scopus databases and yielded 35 studies containing the influence of MK on SARS-CoV-2. Ultimately, MK appears to be worth being used as an adjuvant therapeutic and prophylactic drug against SARS-CoV-2. Nevertheless, more clinical trials are required to accurately investigate its effectiveness.

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IssueVol 20 No 4 (2021) QRcode
SectionReview Article(s)
COVID-19 Leukotriene antagonists Leukotriene D4 receptor Montelukast SARS-CoV-2

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How to Cite
Sharifinejad N, Sharafian S, Salekmoghadam S, Tavakol M, Qorbani M. Montelukast and Coronavirus Disease 2019: A Scoping Review. Iran J Allergy Asthma Immunol. 2021;20(4):384-393.