Nebulized Ipratropium Bromide-induced Anisocoria: Why Is Anisocoria Observed?
Nebulization Induced Anisocoria
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Abstract
Pharmacological anisocoria is a rare but benign condition. This paper presents an eleven-year-old patient with asthma who developed ipratropium bromide-associated anisocoria during nebulizer treatment. Hypotheses regarding the possible causes of anisocoria are discussed and precautions to be taken during treatment are presented. To prevent the development of anisocoria, it was found that it is important to use the appropriate mask during nebulizer treatment, to place the mask on the face properly, and, if possible, to administer drugs by closing the eyes. Further, it is recommended that patients undergo an ophthalmological examination before discharge and that they and their families be informed that the condition is temporary.
1. Pennington KM, St Louis EK. "Don't believe your eyes "Ipratropium induced mydriasis: A case report and review of the literature. Gen Med (Los Angel). 2016;4(3):255.
2. Chaudhry P, Friedman DI, Yu W. Unilateral pupillary mydriasis from nebulized ipratropium bromide: A false sign of brain herniation in the intensive care unit. Indian J Crit Care Med. 2014;18(3):176-7.
3. Kokulu K, Öner H, Özen C, Eroğlu SE, Altunok İ, Akça HŞ. Pharmacologic anisocoria due to nebulized ipratropium bromide: A diagnostic challenge. Am J Emerg Med. 2019;37(6):1217.e3-1217.
4. Pejic R, Klaric B. Transient anisocoria in a patient treated with nebulized ipratropium bromide. Am J Ophthalmol Case Rep. 2017;7:11-13.
5. Bisquerra RA, Botz GH, Nates JL. Ipratropium-bromide-induced acute anisocoria in the intensive care setting due to ill-fitting face masks. Respir Care. 2005;50(12):1662-4.
6. Quinonez ZA, Ravula NR Anisocoria in a 10-month old girl in the immediate preoperative setting: can you proceed with surgery? J Biomed Res. 2011;25(3):224-6.
7. Harer K, Alverson B. Eye-opening etiologies. Hosp Pediatr. 2018;8(5):300-1.
8. Sangwan S, Gurses BK, Smaldone GC. Face masks and facial deposition of aerosols. Pediatr Pulmonol. 2004;37(5):447-52.
9. Gundoğan NU, Yazıcı AC, Ogus E, Simsek A. An original study for evaluating the correlation between handedness and eye dominance by different methods. J Med 2007;27:155-63.
10. Iosson N. Nebulizer-associated anisocoria. N Engl J Med. 2006;354(9):e8.
2. Chaudhry P, Friedman DI, Yu W. Unilateral pupillary mydriasis from nebulized ipratropium bromide: A false sign of brain herniation in the intensive care unit. Indian J Crit Care Med. 2014;18(3):176-7.
3. Kokulu K, Öner H, Özen C, Eroğlu SE, Altunok İ, Akça HŞ. Pharmacologic anisocoria due to nebulized ipratropium bromide: A diagnostic challenge. Am J Emerg Med. 2019;37(6):1217.e3-1217.
4. Pejic R, Klaric B. Transient anisocoria in a patient treated with nebulized ipratropium bromide. Am J Ophthalmol Case Rep. 2017;7:11-13.
5. Bisquerra RA, Botz GH, Nates JL. Ipratropium-bromide-induced acute anisocoria in the intensive care setting due to ill-fitting face masks. Respir Care. 2005;50(12):1662-4.
6. Quinonez ZA, Ravula NR Anisocoria in a 10-month old girl in the immediate preoperative setting: can you proceed with surgery? J Biomed Res. 2011;25(3):224-6.
7. Harer K, Alverson B. Eye-opening etiologies. Hosp Pediatr. 2018;8(5):300-1.
8. Sangwan S, Gurses BK, Smaldone GC. Face masks and facial deposition of aerosols. Pediatr Pulmonol. 2004;37(5):447-52.
9. Gundoğan NU, Yazıcı AC, Ogus E, Simsek A. An original study for evaluating the correlation between handedness and eye dominance by different methods. J Med 2007;27:155-63.
10. Iosson N. Nebulizer-associated anisocoria. N Engl J Med. 2006;354(9):e8.
| Files | ||
| Issue | Vol 20 No 1 (2021) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/ijaai.v20i1.5420 | |
| Keywords | ||
| Anisocoria Child Ipratropium bromide Pediatric emergency medicine | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Derinoz-Guleryuz O, Fidanci İlknur, Men-Atmaca Y. Nebulized Ipratropium Bromide-induced Anisocoria: Why Is Anisocoria Observed?. Iran J Allergy Asthma Immunol. 2021;20(1):125-128.
