Case Report
  

A Rare Case of Hyper IgE Syndrome with Vocal Cords Involvement

Abstract

Hyperimmunoglobulin E syndrome (HIGE) is considered as a phagocytic or a newly classified complex and heterogeneous primary immunodeficiency disease with symptoms such as increased levels of immunoglobulin E, eczema, and, recurrent lung and skin infections. In this paper, we have presented a rare case of this syndrome. A 9-year-old Iranian girl presented with a history of pruritic maculopapular rash who was eventually diagnosed as a case of HIGE. In her recent admission, she had dysphonia, stridor and huge cauliflower cutaneous lesions on her neck, finger and vocal cords, which did not respond to intravenous antibiotics, and ultimately required surgical removal.

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IssueVol 18, No 2 (2019) QRcode
SectionCase Report(s)
DOI https://doi.org/10.18502/ijaai.v18i2.926
Keywords
Cauliflower Hyperimmunoglobulin E syndrome Immunodeficiency Lesions
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Sharafian S, Movahedi M, Kalantari A, Parvaneh N, Gharagozlou M. A Rare Case of Hyper IgE Syndrome with Vocal Cords Involvement. Iran J Allergy Asthma Immunol. 2019;18(2):225-229.