Successful Treatment of Insulin Allergy with Desensitization Therapy: A Case Report and Literature Review

  • Hamza Elfekih Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
  • Faten Hadjkacem Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
  • Mouna Elleuch Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
  • Dorra Ghorbel Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
  • Nadia Charfi Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
  • Fatma Mnif Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
  • Nabila Rekik Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
  • Mouna Mnif Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
  • Mohamed Abid Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia
Keywords: Desensitization, Immunologic, Diabetes mellitus, Hypersensitivity, Insulin

Abstract

Insulin therapy is an essential treatment for type 1 and uncontrolled type 2 diabetes mellitus (DM). Hypersensitivity reactions have been described since the first administration of insulin, the same as any other therapy. Despite being a rare situation nowadays, it requires careful intra-hospital monitoring and multidisciplinary management. Here, we present a case of a 57-year-old patient with type 2 DM, an average glycemic control, and both penicillin and insulin allergy. Heunderwent a desensitization protocol which allowed successfully dismiss him with intermediate-acting insulin.

Author Biographies

Hamza Elfekih, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Department of Endocrinology Diabetology

Faten Hadjkacem, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Department of Endocrinology Diabetology

Mouna Elleuch, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Department of Endocrinology Diabetology

Dorra Ghorbel, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Department of Endocrinology Diabetology

Nadia Charfi, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Hedi Chaker university hospital, Sfax

Fatma Mnif, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Department of Endocrinology Diabetology

Nabila Rekik, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Hedi Chaker university hospital, Sfax

Mouna Mnif, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Hedi Chaker university hospital, Sfax

Mohamed Abid, Department of Endocrinology and Diabetology, Hedi Chaker University Hospital, Sfax, Tunisia

Hedi Chaker university hospital, Sfax

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Published
2019-10-23
How to Cite
1.
Elfekih H, Hadjkacem F, Elleuch M, Ghorbel D, Charfi N, Mnif F, Rekik N, Mnif M, Abid M. Successful Treatment of Insulin Allergy with Desensitization Therapy: A Case Report and Literature Review. Iran J Allergy Asthma Immunol. 18(5):572-583.
Section
Case Report(s)