Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 4 1 2005 03 15 15 22 Majid Mahmoodi Saeid Rajabalian Alireza Fekri Iraj Esfiarpour 2015 10 01 This study investigated the in vitro production of interferon-γ, interleukin (IL)-10, IL-12, and IL-13, after antigenic stimulation of the cells (with Leishmania antigen and lipopolysaccharide) using whole blood from patients with cutaneous leishmaniasis lesions caused by Leishmania tropica and in volunteers with history of cutaneous leishmaniasis. ELISA results showed that the mean production of interferon-γ by cells of whole blood in patients with lesions in response to Leishmania antigen was significantly lower than corresponding values in volunteers with history of cutaneous leishmaniasis (P< 0.05) and significantly higher levels of IL-10 production in patients with lesions were observed compared with cured volunteers of the disease (P https://ijaai.tums.ac.ir/index.php/ijaai/article/view/94 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/94/94