Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 1 1 2000 01 15 41 43 N. Sheikh M. Tavakol 2015 10 01 Although research on adult subjects has demonstrated a positive correlation between humor and increased concentrations of secretory immunoglobulin A, the literature has not addressed whether humor might have a similar effect on children. Fifth grade student volunteers (n= 190) at elementary schools in Hamadan were randomly assigned to treatment and control groups. The study compared secretory immunoglobulin A levels collected before and after the treatment group subjects (n=105) participated in a humorous program and the control group sub¬jects (n-85) participated in an educational non-humorous presentation. Concen¬trations of immunoglobulin A were increased in those who observed a humorous presentation. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/8 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/8/8