Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 14 3 2015 10 18 338 340 EN Soheyla Alyasin Department of Allergy and Clinical Immunology, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Maryam Khoshkhui Department of Allergy and Clinical Immunology, Shiraz University of Medical Sciences, Shiraz, Iran Reza Amin Department of Allergy and Clinical Immunology, Shiraz University of Medical Sciences, Shiraz, Iran 2015 10 18 2015 10 18 Churg-Strauss syndrome (CSS) is a granulomatous small vessel vasculitis . It is characterized by asthma, allergic granulomatosis and vasculitis . This syndrome is rare in children. A 5 years old boy was admitted with cough, fever and dyspnea for 2 weeks. On the basis of  laboratory data (peripheral eosinophilia), associated with skin biopsy, and history of CSS in his sister, this disease was eventually diagnosed. The patient had good response to corticosteroid.In  every  asthmatic  patient  with  prolonged  fever, eosinophilia  and  multisystemic involvment, CSS should be considered. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/576 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/576/461