Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 12 2 2013 06 15 176 181 EN Hassan Abolhassani Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran Asghar Aghamohammadi Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran Sarvenaz Pourjabbar Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran Mohammad Salehi Sadaghiani Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran Sina Nikayin Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran Anahita Rabiee Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran Amir Imanzadeh Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran Javad Mahmmoodi Gharaei Department of Psychiatric, Rozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Mohammad Arbabi Department of Psychiatric, Rozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Nima Rezaei Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran AND Molecular Immunology Research Center; and Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2015 10 16 Primary immunodeficiency diseases (PID) consist of a group of long-term illnesses which had permanent psychiatric effects on the patients and their parents. This study was designed to find out the most important origins and aspects of stressor in parents of PID patients.To assess the  impact of  psychiatric aspects in parents  of PID  patients, a valid and reliable questionnaire was compiled based on patients' complaints and consulting professionals in PID and psychology. Fathers of 26 PID patients (17 male and 9 female) were enrolled in this study. According to the result of this study, anxiety for long duration of disease of child (mean score= 4.42), anxiety for incurable diseases of child (mean score=4.23) and anxiety for side effects and complication of treatments on child (mean score=4.08) were the most important stressors of parents. The  comparison  between  specific PID  groups  showed  that  there  were  significant differences between total score of groups (XLA= 92.8±31.2, CVID=78.7±19.5 and other types of PID=  90.7±22.5, p-value =0.37). Survey for finding fundamental stressors and continuation of psychological counseling are necessary to achieve successful management of PID patients and their parents. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/516 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/516/517