Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 7 4 2008 12 15 235 238 Alborzi Abdolvahab Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shir Mostafavi Nasser Isfahan University of Medical Sciences, Isfahan, Iran Pouladfar Gholam Reza Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shir 2015 10 01 In chronic granulomatous disease (CGD) patients, esophageal stricture is a rare complication and the treatment of choice is still controversial. There are few reports of successful therapy with antibiotics, corticosteroids, multiple balloon dilatations or their combination. We report a 3-three-year-old Iranian boy with recurrent esophageal obstruction due to CGD. The patient transiently responded to dilatation in one occasion and at another time to short term steroid therapy. We observed an excellent response when long term and high dose of corticosteroid was administered. It showed that a long term and high dose steroid therapy is more effective than a short term in a patient with CGD and esophageal stricture. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/225 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/225/225