Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 6 4 2007 12 15 219 221 Payam Tabarsi Mehdi Mirsaeidi Shirin Karimi Behzad Banieghbal Nahal Mansouri Mohammad Reza Masjedi Davood Mansouri 2015 10 01 Chronic Granulomatous Disease (CGD) is a rare primary immunodeficiency disease. Although the most affected patients are diagnosed in childhood, there are several reports of the disease presenting in adult patients. Here we present a 40 years old man who was admitted in hospital due to respiratory symptoms and ground glass pattern in high resolution computed tomography of lung. Open lung biopsy revealed lymphocytic bronchiolitis. Because of past medical history of granulomatous lesion in lung and recurrent abscesses of skin and soft tissue, NBT test was conducted which its result revealed that the disorder was compatible with CGD and then it was confirmed by fluorescent cytometry. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/189 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/189/189