Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 5 1 2006 03 15 35 37 Mohammad Gharagozlou Fariborz Zieh Parviz Tabatabaei Gholamreza Zamani 2015 10 01 There are few reports about congenital indifference to pain or Hereditary and Sensory Autonomic Neuropathy (HSAN). Several investigations for pathophysiology of this syndrome have been performed and different classifications about it. In this report we present a case of HSAN type II with general absence of pain and self amputations and leprosy–like damage of extremities which was suspected to be phagocytic immunodeficiency due to past history of repeated ulcer and abscess formation. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/131 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/131/131