Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 5 1 2006 03 15 29 31 "Reza Farid Ramin Ghasemi Mahmood Baradaran-Rahimi Farahzad Jabbari Javad Ghaffari Hooshang Rafatpanah " 2015 10 01 Allergen immunotherapy involves the administration of gradually increasing quantities of specific allergens to patients with IgE-mediated conditions until a dose is reached that is effective in reducing disease severity from natural exposure. In the present study we evaluated a period of six years immunotherapy allergic rhinitis and allergic asthma patients with positive skin prick test of common aeroallergen. The immunotherapy was performed on 156 patients. One hundred twenty of the cases were allergic rhinitis (80%), 29 cases had allergic asthma and 7 cases were mixed (4.5%). 70% in allergic rhinitis group, 75% in allergic asthma group and 42.8% in mixed group completely improved. Immunotherapy, an older therapeutic method, has now been updated, and with appropriate indications, precautions and methods, has been clearly shown to be effective in the treatment of allergic rhinitis and in some cases of asthma and insect hypersensitivity. https://ijaai.tums.ac.ir/index.php/ijaai/article/view/129 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/129/129