Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 5 1 2006 03 15 17 22 Ebrahim Razi Gholam Abbass Moosavi 2015 10 01 Corticosteroids are recommended for emergency management of an asthmatic attack. This study was designed to compare the effectiveness of oral and intramuscular steroid on spirometric results in acute asthma. We performed a randomized trial involving 88 adults, aged 15-70 years, with acute exacerbation of asthma requiring treatment with steroids. All had been treated with standard bronchodilator regimens and then received oral prednisone, 40 mg/day for 7 days, or 40 mg/day intramuscular triamcinolone long acting (LA) for 3 days. Spirometric variable and percentage of change to baseline forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1) after treatment were calculated. Baseline characteristic were comparable in the oral prednisone group (n=44) and in the intramuscular triamcinolone LA groups (n=44). After 7 days of treatment, the mean (SD) FEV1 and FVC in both groups improved statistically over baseline values (P https://ijaai.tums.ac.ir/index.php/ijaai/article/view/127 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/127/127