Tehran University of Medical Sciences Iranian Journal of Allergy, Asthma and Immunology 1735-1502 4 3 2005 09 15 129 132 Reza Ghaderi Zahra Makhmalbaf 2015 10 01 Atopy can be defined as the genetically determined risk to develop allergic disease. Avoidance of one specific allergen may decrease the risk for sensitization against this allergen, but it will not affect atopy. Our aim was to investigate if exclusive breast-feeding is associated with atopic dermatitis during the first 5 years of life. Data on 200 children were taken from parental-administered questionnaires from a case control study in Birjand - Iran (recruited 2003) comprised of a case (100 children with atopic dermatitis) and a control (100 normal children) subgroup. Outcomes were physician-diagnosed atopic dermatitis (AD) and itchy rash. Data were analyzed by using SPSS package, Chi square and Exact Fisher tests. Thirty-four of the case and 50 of control group were exclusively breast-fed, whereas 6 of the case and 2 of control group were exclusively cow milk-fed. These differences were statistically significant. (P https://ijaai.tums.ac.ir/index.php/ijaai/article/view/111 https://ijaai.tums.ac.ir/index.php/ijaai/article/download/111/111